Vitamin B6, Pyridoxine

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Vitamin B6, Pyridoxine

Vitamin B6, also known as pyridoxine, plays a role in the creation of antibodies in the immune system. It helps maintain normal nerve function and acts in the formation of red blood cells. It is also required for the chemical reactions of proteins. The higher the protein intake, the more need there is for vitamin B6.

Pyridoxal phosphate (PLP) is the active form and is a cofactor in many reactions of amino acid metabolism, including transamination, deamination, and decarboxylation. It also is necessary for the enzymatic reaction governing the release of glucose from glycogen.

For digestion to occur, vitamin b must be broken down, and separated into its 3 main components pyridoxine, pyridoxal, and pyridoxamine. This occurs in the intestinal brush border, via enzymatic reactions. Absorption occurs primarily in the jejunum (middle portion of small intestine, connects with the duodenum (first portion) and the ileum (last portion) of the small intestine) by passive diffusion. In the intestine, PN is converted to pyridoxine phosphate (PNP), PL is converted to pyridoxal phosphate (PLP), and PNP is often converted to PLP, while PM remains the same, and composes about 15% of the vitamers in the blood. 60% of vitamin b 6 found in the blood is PLP. In order for PLP to cross the cell membrane it must be broken down to PL. The liver stores approximately 10% of vitamin b 6, while muscles store the most at 80%. Other storage houses are the kidneys, brain, and red blood cells.

Vitamin B6 acts as a coenzyme for approximately 100 essential chemical reactions. These include protein and glycogen metabolism, proper action of steroid hormones, pyruvate production, production of red blood cells and much more. It assists in many decarboxylation reactions (removal of carboxyl group) for the production of several compounds such as glutamate (major neurotransmitter of the central nervous system). It also is of great use to the immune system in that it helps hemoglobin production and increases the amount of O2 carried by it. Also, it assists white blood cell production, all of which is vital for your health. In all, vitamin B6 is essential for cellular functions and growth due to its involvement in important metabolic reactions.
Pyridoxine is additionally responsible for the synthesis of many compounds. For example, niacin depends on a PLP dependant reaction to be broken down. Others required by Pyridoxine for synthesis are amino acid histidine, carnitine, nitrogen containing compounds, CoA and glycine taurine, dopamine, and helps regulate neurotransmitters, playing a major role in the nervous system.

Signs of deficiency are fatigue, glossitis (sore tongue) sleepiness, dermatitis (skin inflammation), neurological problems, eye problems, seizers, kidney and heart diseases, and convulsions in infants. Tryptophan and niacin synthesis will be slowed as well. People more likely to be deficient in this are infants, old people, excessive alcohol consumption, those on a variety of drugs, and certain medical conditions. High protein intake and stress may inhibit this as well. Also, a deficiency in B6 has been shown to increase the amino acid homocysteine found in the blood.

We provide high quality vitamin B6 at a preferable price. The product should be stored in cool, ventilated place where it can be kept from water as well as the high temperature. It is packed in special cases, 25kg a case.

Related Names
VB6 | Pyridoxine Hydrochloride | Water-soluble Vitamin | Water Soluble Vitamin

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As a major vitamin B6, pyridoxine manufacturer and supplier in China, we also provide vitamin B1, thiamine, bentonite, choline chloride, betaine hydrochloride, feed grade yeast powder, and much more.