IUPAC name: pyridine-3-carboxylic acid
CAS number: 59-67-6
Other names: BETA-PICOLINIC ACID; AKOS BBS-00003719; ACIDUM-NICOTINICUM; 3-PICOLINIC ACID; 3-CARBOXYPYRIDINE; RARECHEM AL BO 0217; TIMTEC-BB SBB004279123.11; 3-Carboxy Pyridine; Pyridine -3-Carloxylic acid; Niacin; pyridine-3-carboxylate; pyridine-3-carboxylic acid
Molecular formula: C6NH5O2
Molar mass: 123.1094 g mol-1
Exact mass: 123.032028409 g mol-1
Appearance: white, translucent crystals
Density: 1.473 g cm-3
Melting point: 237 °C, 510 K, 458 °F
Solubility in water: 18 g L-1
Vitamin B3 (also known as niacin, nicotinic acid and vitamin PP) is an organic compound and one of the forty to eighty essential human nutrients. This colorless, water-soluble solid is a derivative of pyridine, with a carboxyl group (COOH) at the 3-position.
In the human body, niacin is broken down to Nicotinamide adenine dinucleotide phosphate (NADP), and nicotinamide adenine dinucleotide (NAD). These are the primary forms which niacin functions within the body. In the intestine, NAD and NADP may be hydrolyzed to release free nicotinamide. This can be absorbed in the stomach, but primarily in the small intestine. Most of the niacin in the blood is found as nicotinamide, a small amount of the time as nicotinic acid. Niacin assists in the functioning of the digestive system, skin, and nerves. Almost 200 enzymes require NAD and NADP to function. NADP assists with fatty acid synthesis, cholesterols and steroid Synthesis and oxidation of glutamate. It is important for the conversion of food to energy. It is also involved in both DNA repair, and the production of steroid hormones in the adrenal gland.
Deficiency of niacin often results in a condition known as pellagra. The side effects are known as four d's; dermatitis (inflammation of skin), dementia (a mental disorder characterized by a general loss of intellectual abilities involving impairment
of memory, judgment and abstract thinking as well as changes in personality), diarrhea, and death. Dermatitis is much like a sunburn at first and appears on areas exposed to sun such as the face and neck and on the extremities such as the back of the hands, wrists, elbows, knees, and feet. Some neurological problems are paralysis of extremities, and dementia (the second D) or delirium. Several gastrointestinal problems may occur such as nausea, vomiting, and diarrhea (the third D).
Widely used as food additive and medicine intermediate, our vitamin B3 is offered with high quality and competitive price. Located in Cangzhou of China, our company is near Tianjin Port, thus ensures convenient transportation. What is more, the raw materials we needed is very near, thus saves quite a lot of cost. Offering best service, our company is very competitive in the market.
VB3 | Pantothenic Acid | Nicotinic Acid | Anti-black Tongue Factor
Tianyu Feed Additive is an experienced vitamin B3, niacin manufacturer based in China. We offer a wide range of products including betaine hydrochloride, titanium dioxide, choline chloride, feed grade yeast powder, and more.