IUPAC name: 2-Methylnaphthalene-1,4-dione
CAS number: 58-27-5
Other names: Menaphthone; Vitamin K3; β-Methyl-1,4-naphthoquinone; 2-Methyl-1,4-naphthodione; 2-Methyl-1,4-naphthoquinone;Menadione (1.05793); Vitamin K2(0); Menadione; Vitamin K_3; 2-Methyl-1,4-dihydronaphthalene-1,4-dione
Molecular formula: C11H8O2
Molar mass: 172.18 g mol−1
Appearance: white power
Melting point: 105–107 °C
Boiling point: 304.5 °C at 760mmHg
Solubility in water: Insoluble
Flash point: 113.8 °C
Vitamin K is a group of structurally similar vitamins. It is fat soluble and plays a critical role in blood clotting. It regulates blood calcium levels and activates at least 3 proteins involved in bone health. Menadione is a synthetic chemical compound sometimes used as a nutritional supplement because of its vitamin K activity. Low dose menadione is used as an inexpensive micronutrient for livestock. Forms of menadione are also included in some pet foods as a source of vitamin K. It is used in the treatment of Hypoprothrombinemia.
Vitamin K is an essential fat-soluble micronutrient, which is needed for a unique post-translational chemical modification in a small group of proteins with calcium-binding properties. Thus far, the unequivocal role of vitamin K in health is in the maintenance of normal coagulation. The vitamin Kdependent coagulation proteins are synthesized in the liver and comprise factors II, VII, IX, and X, which have a haemostatic role (i.e. they are procoagulants that arrest and prevent bleeding), and proteins C and S, which have an anticoagulant role (i.e. they inhibit the clotting process). Despite this duality of function, the overriding effect of nutritional vitamin K deficiency is a bleeding tendency caused by the relative inactivity of the procoagulant proteins. Vitamin K-dependent proteins synthesized by other tissues include the bone protein osteocalcin and matrix Gla protein, though their functions remain to be clarified.
Vitamin K should be stored in cool, ventilated place where it can be kept from water as well as light. Keep it in original package. Please use it in 12 months.
Hemodal | Itykinone | Menadione Sodione Bisulfite | Coagulant
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