Name: choline chloride
IUPAC name: 2-hydroxy-N,N,N-trimethylethanaminium chloride, (2-hydroxyethyl)trimethylammonium chloride, (β-Hydroxyethyl)trimethylammonium chloride
CAS number: 67-48-1
Molecular formula: HOCH2CH2N(CH3)3Cl
Molecular weight: 139.63
Solubility in water: very solute(more than 650g/l)
Appearance: white crystalline solid
Our product choline chloride 98% crystal not only offers a high purity up to 98% but also best quality. 2% drying loss at most, no more than 300ppm TMA, no more than 20.0ppm heavy metal and other properties you could think of are ensured. Besides, about particle size, at least 98% of the product could pass 20mesh. Choline chloride has neither explosive nor oxidizing properties due to its molecular structure.
Choline chloride is the salt of the naturally occurring choline, the pre-stage of the neurotransmitter acetylcholine, which is important for mnemonic and thought-processes. Choline occurs naturally in fungi, hop and kingcups and as integral part of lecithin. It is a common food additive in animal husbandry. Choline chloride is mass produced and is an important additive in feed especially for chickens where it accelerates growth. In fact, it has prominence effects on improving the quality and quantity of eggs and meat. On the contrary, shortage of choline results to fatty liver diseases, retarded growth, reduced egg-laying rate and increased mortality. Besides, choline chloride is also used as intermediate of biology medicine and pesticide.
Animal studies with choline chloride show a low acute toxicity after oral uptake (with a range of LD50s of 3150 –≥5000 mg/kg bw determined in different studies). No acute toxicity attributable to choline was observed in humans following oral doses of ≥3000 mg choline magnesium trisalicylate/day. Evidence from animal studies and from human exposure indicates that choline chloride has low toxicity, is not mutagenic and has no developmental toxicity. This is not unexpected in view of its presence in the diet and its production in metabolic processes in the body. It fulfils key roles in nerve transmission, cell membrane integrity, and lipid metabolism.
Limited animal data are available on effects on fertility, but the normal exposure of humans to appreciable amounts of choline chloride both from the diet and formed from normal metabolic processes, would argue against it having any significant adverse effects on fertility. This is supported by the fact that it has been widely used as an animal feed additive for decades with no apparent adverse effects being noted on fertility. Choline chloride is readily biodegradable according to OECD-criteria (MITI-I Test; BOD measurements) reaching 93 % degradation within 14 days.
The choline chloride 98% crystal should be stored in cool, ventilated place where it can be kept from water as well as the high temperature. Besides, it should be equipped with dehumidification equipment for its hygroscopicity. To ensure the activity, you had better use it in 15 months. The product is packed with plastic lining or white P.P .bag, 25kg in one bag. Offering best service, we guarantee that it could be shipped in 15 working days.
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As an experienced choline chloride 98% crystal manufacturer in China, we provide a vast range of products including betaine anhydrous, feed grade yeast powder, caustic soda flake, vitamin B12, cyanocobalamin, and more.